Publications 2010-2023






308A)   Assaf, K. I.; Nau, W. M. Large anion binding in water. Org. Biomol. Chem., 2023, DOI.               

307A)   Chen, Y.; Barba-Bon, A.; Grüner, B.; Winterhalter, M.; Aksoyoglu, M. A.; Pangeni, S.; Ashjari, M.; Brix, K.; Salluce, G.; Folgar-Cameán, Y.; Montenegro, J.; Nau, W. M., Metallacarborane Cluster Anions of the Cobalt Bisdicarbollide-Type as Chaotropic Carriers for Transmembrane and Intracellular Delivery of Cationic Peptides. J. Am.Chem. Soc. 2023.

306A)  Paatelainen, M., Lahikainen, M., Berdin, A., Kuntze, K., Nau, W. M.,  Nonappa, Priimagi, A., Hydrogel Lasers Via Supramolecular Host–Guest Complexation. Adv. Optical Mater. 2023, 2300232.

305A)   S. Moorthy, H. Lambert, N. Mohan, T. Schwarzlose, W. M Nau, E.  Kalenius, T.-C. Lee, Noncovalent Modulation of Chemoselectivity in the Gas Phase Leads to a Switchover in Reaction Type from Heterolytic to Homolytic to Electrocyclic Cleavage Angew. Chem. Int. Ed. 2023, e202303491.

304A)  M. H. Jacob, R. N. D´Souza, A. I. Lazar. W. M. Nau,Diffusion-Enhanced Förste Resonance Energy Transfer in Flexible Peptides: From the Haas-Steinberg Partial Differential Equation to a Closed Analytical Expression Polymers. 2023, 15, 705.

303A)  X. Hu, J. Zhao, Y. Zhao, H. Zhang, Q. Wang, B. Ge, X. Wang, H. He, W. M. Nau, X. Wang, F. Huang, Direct Observation and Real-Time Tracking of an Extraordinarily Stable Folding Intermediate in Mitotic Arrest Deficient Protein 2 Folding by Single-Molecule Fluorescence Resonance Energy Transfer, J. Phys. Chem. Lett., 2023, 14, 763-769.

302A)  F.J. R. Mejías, S. He, R. M. Varela, J. M. G. Molinillo, A. Barba-Bon, W. M. Nau and F. A. Macías, Stability and pKa Modulation of Aminophenoxazinones and Their Disulfide Mimics by Host–Guest Interaction with Cucurbit[7]uril. Direct Applications in Agrochemical Wheat Models, J. Agric. Food Chem., 2023, 17, 480-487.





301C)  J. Zhang, D. Gabel, K. I. Assaf, W. M. Nau. A Fluorescein-Substituted Perbrominated Dodecaborate Cluster as an Anchor Dye for Large Macrocyclic Hosts and Its Application in Indicator Displacement Assays. Org. Lett2022, 24, 9184-9188.

300A)   A. Barba-Bon, G. Salluce, I. Lostalé-Seijo, K.I. Assaf, A. Hennig, J. Montenegro, W.M. Nau, Boron Clusters as Broadband Membrane Carriers.  Nature2022, 603, 637-642.

299A)  M. Masi, J. Vergalli, I. Ghai, A. Barba-Bon, T. Schembri, W. M. Nau, D. Lafirre, M. Winterhalter, J.-M. Pagès. Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane. Commun Biol. 2022, 5, 1059.

298C) M. Nilam, S. Karmacharya, W. M. Nau, A. Hennig, Proton-Gradient-Driven Sensitivity Enhancement of Liposome-Encapsulated Supramolecular Chemosensors. Angew. Chem. Int. Ed. 2022, e202207950.

297A) B. Xiao, S. He, M. Sun, J. Zhou, Z. Wang, Y. Li, S. Liu, W. M. Nau, S. Chang, Dynamic Interconversions of Single Molecules Probed by Recognition Tunneling at Cucurbit[7]uril-Functionalized Supramolecular Junctions. Angew. Chem. Int. Ed. 2022, e202203830.

296A) S. Bhattacharya, A. Barba-Bon, T. A. Zewdie, A. B. Müller, T. Nisar, A. Chmielnicka, I.A. Rutkowska, C. J. Schürmann, V. Wagner, N. Kuhnert, P. J. Kulesza, W. M. Nau, U. Kortz, Discrete, Cationic Palladium(II)-Oxo Clusters via f-Metal Ion Incorporation and their Macrocyclic Host-Guest Interactions with Sulfonatocalixarenes. Angew. Chem. Int. Ed. 2022, e202203114.

295A)    F. N. Tehrani, K. I. Assaf, R. Hein, C.M. E. Jensen, T. C. Nugent, W. M. Nau,  Supramolecular Catalysis of a Catalysis-Resistant Diels-Alder Reaction: Rapid Dimerization of Cyclopentadiene inside Cucurbit[7]uril. ACS Catal. 2022, 12, 2261−2269.

294A)   T. Marei, M. K. Al-Joumhawy, M. A. Alnajjar, W. M. Nau,  K.I. Assaf and D. Gabel. Binding affinity of aniline-substituted dodecaborates to cyclodextrins. Chem. Commun., 2022, 58, 2363-2366.

293A)    A. Norouzy,  A. I. Lazar,  M. H. Karimi‑Jafari, R. Firouzi, W. M. Nau. Electrostatically induced pKa shifts in oligopeptides: the upshot of neighboring side chains. Amino Acids, 2022, 54, 277–287





292A)   M. Molkenthin, W. M. Nau,  B. J. Nachtsheim. Efficient Hydro‐ and Organogelation by Minimalistic Diketopiperazines Containing a Highly Insoluble Aggregation‐Induced, Blue‐Shifted Emission Luminophore**. Chem. Eur. J. 202127, 16488-16497.

291A)    X. Wang, X. Ma,  C. Liu, B. Ge, H. He, Q. Dai, Z. Zhang, J. Yu, W. M. Nau, F. Huang. Self-assembled Theranostic Microcarrier Targeting Tumor Cells with High Metastatic Potential. Materials & Design, 2021, 212 ,110196.

290A)   M. A. Alnajjar, W. M. Nau, A. Hennig, A reference scale of cucurbit[7]uril binding affinities.  Org. Biomol. Chem., 2021, 19, 8521-8529.

289A)    N. Saleh, S. Al-Jassabi, A. Eid, W. M. Nau, Cucurbituril Ameliorates Liver Damage Induced by Microcystis aeruginosa in a Mouse Model, Front. Chem. 2021, doi: 10.3389/fchem.2021.660927.

288A)    S. Pangeni, J. Prajapati, B. Dahyabhai, A. Jayesh, N. Mohamed, W. M. Nau, U. Kleinekathöfer, M. Winterhalter, Large Peptide Permeation Through a Membrane Channel: Understanding Protamine Translocation Through CymA from Klebsiella Oxytoca Angew. Chem. Int. Ed. 202160, 8089-8094.

287A)    Z. Hou, W. M. Nau, R. Hoogenboom, Reversible covalent locking of a supramolecular hydrogel via UV-controlled anthracene dimerization, Polymer Chem. 2021, 12, 307–315.

286A)    H. He, L. Liu, X. Chen, Q. Wang, X. Wang, W. M. Nau, F. Huang, Carbon Dot Blinking Enables Accurate Molecular Counting at Nanoscale ResolutionAnal. Chem. 202193, 3968–3975.

285A)    Y.-C. Pan, A. Barba-Bon, H. W. Tian, F. Ding, A. Hennig, W. M. Nau, D. S. Guo, An Amphiphilic Sulfonatocalix[5]arene as a Novel Activator for Membrane Transport of Lysine-rich Peptides and ProteinsAngew. Chem. 2021133, 1903–1910; Angew. Chem. Int. Ed. 202160, 1875–1882.

284A)   M. Nilam, S. Collin, S. Karmacharya, A. Hennig, W. M. Nau, Membrane Permeability and its Activation Energies in Dependence on Analyte, Lipid, and Phase Type Obtained by Fluorescent Artificial Receptor Membrane Assay, ACS Sensors 20216, 175–182.





283A)  S. He, A. Zhiti, A. Barba-Bon, A. Hennig, W. M. Nau, Real-Time Parallel Artificial Membrane Permeability Assay based on Supramolecular Fluorescent Artificial ReceptorsFontiers Chem. 20208, 806; doi: 10.3389/fchem.2020.00806

282A)  A. Hennig, W. M. Nau. Interaction of Cucurbit[7]uril with Protease Substrates: Application to Nanosecond Time-Resolved Fluorescence Assays. Frontiers Chem. 2020,8,806, doi:10.3389/fchem.2020.00806.

281A)  F. Biedermann, G. Ghale, A. Hennig, W. M. Nau. Fluorescent Artificial Receptor-based Membrane Assay (FARMA) for Spatiotemporally Resolved Monitoring of Biomembrane Permeability. Communic. Biol. 2020,3,383.

280A)  M. Shahabi, R. Hajihosseini, W. M. Nau, K. Akbari Noghabi, A. Norouzy. Augmenting Peptide Flexibility by Inserting Gamma-Aminobutyric Acid (GABA) in Their Sequence. Int. J. Pept. Res. Ther. 202026, 2633-2640.

279A)  M. Huang, M. Sun, X. Yu, S. He, S. Liu, W. M. Nau, Y. Li, T. Wu, Y. Wang, S. Chang, J. He. Reliably Probing the Conductance of a Molecule in a Cavity via van der Waals Contacts. J. Phys. Chem. C 2020, 29, 16143–16148.

278A)  K. I. Assaf, H. Abed Alfattah, A. F. Eftaiha, S. K. Bardaweel, M. A. Alnajjar, F. A. Alsoubani, A. K. Qaroush, M. I. El-Barghouthi, W. M. Nau. Encapsulation of Ionic Liquids inside Cucurbiturils. ChemistrySelect 202018, 2120–2128.

277A)  M. Nilam, C. Huang, S. Karmacharya, G. H. Aryal, L. Huang, W. M. Nau, K. I. Assaf. Host-Guest Complexation Affects Perylene-Based Dye Aggregation. ChemistrySelect 20205, 5850–5854.

276A)  K. I. Assaf, J. Holub, E. Bernhardt, J. M. Oliva-Enrich, M. I. Fernández Pérez, M. Canle Lopez, J. A. Santaballa, J. Fanfrlík, D. Hnyk, W. M. Nau. Face-Fusion of Icosahedral Boron Hydride Increases Affinity to γ-Cyclodextrin: closo,closo-[B21H18] as an Anion with Very Low Free Energy of Dehydration. ChemPhysChem 202021, 971–976.

275B)  A. Hennig, W. M. Nau. Cucurbituril-Based Sensors and Assays. in “Cucurbiturils and Related Macrocycles”, Ed.: K. Kim, RSC Press, Cambridge, UK, 2020, 121–149.

274B)  K. I. Assaf, W. M. Nau. Cucurbituril Properties and the Thermodynamic Basis of Host-Guest Binding. in “Cucurbiturils and Related Macrocycles”, Ed.: K. Kim, RSC Press, Cambridge, UK, 2020, 54–85.

273A)  A. Wagner, K. H. Ly, N. Heidary, I. Szabó, K. I. Assaf, S. J. Barrow, K. Sokołowski, N. Kornienko, M. F. Kuehnel, E. Rosta, I. Zebger, W. M. Nau, O. Scherman, E. Reisner. Host-guest-Chemistry Meets Electrocatalysis: Cucurbit[6]uril on a Au Surface as Hybrid System in CO2 Reduction. ACS Catalysis 202010, 751–761.





272A)  A. Barba-Bon, Y.-C. Pan, F. Biedermann, D.-S. Guo, W. M.  Nau, Werner; A. Hennig, Fluorescence Monitoring of Peptide Transport Pathways into Large and Giant Vesicles by Supramolecular Host-Dye PairsJ. Am. Chem. Soc.2019, 141, 20137–20145.

271C)  S. Zhang, L. Grimm, Z. Miskolczy, L. Biczók, F. Biedermann W. M. Nau, Binding Affinities of Cucurbit[n]urils with CationsChem. Commun.2019, 55, 14131–14134.

270C)  Y.-C. Liu, W. M. Nau, A. Hennig, A Supramolecular Five-Component Relay Switch that Exposes the Mechanistic Competition of Dissociative versus Associative Binding to Cucurbiturils by Ratiometric Fluorescence MonitoringChem. Commun.2019, 55, 14123-14126.

269C)  S. El Anwar, K. I. Assaf, B. Begaj, M. A. Samsonov, Z. Růžičková, J. Holub, D. Bavol, Werner M. Nau, D. Gabel, B. Grüner, Versatile, one-pot introduction of nonahalogenated 2-ammoniodecaborate ions as boron cluster scaffolds into organic molecules; host-guest complexation with g-cyclodextrinChem. Commun.2019, 55, 13669–13672.

268A)  S. J. Barrow, K. I. Assaf, A. Palma, W. M. Nau, O. A. Scherman, Preferential Binding of Unsaturated Hydrocarbons in Aryl–Bisimidazolium•Cucurbit[8]uril Complexes Furbishes Evidence for Small-Molecule π–π InteractionsChem Sci.2019, 10, 10240–10246.

267A)  Y.-C. Liu, S. Peng, L. Angelova, W. M. Nau, A. Hennig, Label-Free Fluorescent Kinase and Phosphatase Enzyme Assays with Supramolecular Host-Dye PairsChemistryOpen2019, 8, 1350–1354.

266A)  D. Maity, K. I. Assaf, C. Hirschhäuser, W. Sicking, W. M. Nau, C Schmuck, A Selective Cucurbit[8]uril-Peptide Beacon Ensemble for Ratiometric Fluorescence Detection of PeptidesChem. Eur. J.2019, 25, 13088–13093.

265R)  K. I. Assaf, D. Das, W. M. Nau, Applications of Cucurbiturils in Medicinal Chemistry and Chemical BiologyFrontiers Chem.2019, 7, 619.

264A)  Y. Wang, X. Wang, X. Ma, Q. Chen, H. He, W. M. Nau, F. Huang, Co-Assembly of Gold Nanoclusters with Nucleic Acids: Sensing, Bioimaging and Gene TransfectionPart. Part. Syst. Charact.2019, 36, 1900281.

263A)    K. I. Assaf, B. Begaj, A. Frank, M. Nilam, A. Mougharbel, U. Kortz, J. Nekvinda, B. Gruner, D. Gabel, W. M. Nau, “High-affinity Binding of Metallacarborane Cobalt Bis(dicarbollide) Anions to Cyclodextrins and Application to Membrane Translocation”J. Org. Chem. 201984, 11790–11798.

262A)  W. K. Chio, W. J. Peveler, K. I. Assaf, S. Moorthy, W. M. Nau, I. P. Parkin, M. Olivo, T.-C. Lee, Selective Detection of Nitroexplosives Using Molecular Recognition within Self-Assembled Plasmonic NanojunctionsJ. Phys. Chem. C2019, 123, 15769–15776.

261A)  A. Farcas, K. I. Assaf, A.-M. Resmerita, L. Sacarescu, M. Asandulesa, P.-H. Aubert, Werner M. Nau, Cucurbit[7]uril-Threaded Poly(3,4-ethylenedioxythiophene): A Novel Processable Conjugated PolyrotaxaneEur. J. Org. Chem.2019, 21, 3442-3450.

260A)  E.-L. Ursu, M. Balan, W. M. Nau, M. Nilam, Y.-C. Liu, A. Farcas, A. Hennig. Synthesis and Photophysical Properties of Inclusion Complexes Between Conjugated Polyazomethines with g-Cyclodextrin and its Tris-O Methylated Derivative. Eur. Polym. J2019, 113, 236–243.

259C)  S. Zhang, K. I. Assaf, C. Huang, A. Hennig, W. M. Nau. Ratiometric DNA Sensing with a Host-Guest FRET Pair.  Chem. Commun. 2019, 55, 671–674.

258A)  W. Wang, X. Wang, C. Xiang, X. Zhou, D. Gabel, W. M. Nau, K. I. Assaf, H. Zhang, Orthogonal Molecular Recognition of Chaotropic and Hydrophobic Guests Enables Supramolecular ArchitecturesChemNanoMat2019, 5, 124–129.





257A)   S. Zhang, Z. Dominguez, K. I. Assaf, M. Nilam, T. Thiele, U. Pischel, U. Schedler, W. M Nau and A. Hennig. Precise Supramolecular Control of Surface Coverage Densities on Polymer Micro- and NanoparticlesChem. Sci.2018, DOI: 10.1039/C8SC03150A .

256A)  S. He, F. Biedermann, N. Vankova, L. Zhechkov, T. Heine, R. E. Hoffman, A. De Simone, T. T. Duignan, W. M. Nau. Cavitation energies can outperform dispersion interactionsNat. Chem.2018, .

255R)   K. I. Assaf and Werner M. Nau, The Chaotropic Effect as an Assembly Motif in ChemistryAngew. Chem. 2018130, 14164–14177. Angew. Chem. Int. Ed. 201857, 13968–13981.

254A)  M. H. Jacob, I. Ghosh, R. N. D’Souza, W. M. Nau. Two Orders of Magnitude Variation of Diffusion-Enhanced Förster Resonance Energy Transfer in Polypeptide Chains.  Polymers 201810, 1079.

253A)  H. S. El-Sheshtawy, S. Chatterjee, K. I. Assaf, M. N. Shinde, W. M. Nau, J. Mohanty, A Supramolecular Approach for Enhanced Antibacterial Activity and Extended Shelf-life of Fluoroquinolone Drugs with Cucurbit[7]uril. Rep., 201818, 13925.

252A)   M. A. Alnajjar, J. Bartelmeß, R. Hein, P. Ashokkumar, M. Nilam, W. M. Nau, K. Rurack, A. Hennig, Rational Design of Boron-dipyrromethene (BODIPY) Reporter Dyes for Cucurbit[7]urilBeilstein J. Org. Chem. 201814, 1961-1971.

251A)  J. Nekvinda, B. Grüner, D. Gabel, W. M. Nau, K. I. Assaf, Host‐Guest Chemistry of Carboranes: Synthesis of Carboxylate Derivatives and Their Binding to CyclodextrinsChem. Eur. J., 2018, 24, 12970–12975.

250A)  M. H. Jacob , R. N. D’Souza, T. Schwarzlose, X. Wang, F. Huang, E. Haas, W. M. Nau. A Method-Unifying View on Loop Formation Kinetics in Peptide and Protein FoldingJ. Phys. Chem. B, 2018122, 4445–4456.

249A)  G. H. Aryal, R. ViK, K. I. Assaf, K. W. Hunter, L. Huang, J. Jayawickramarajah, W. M. Nau. Structural Effects on Guest Binding in Cucurbit[8]uril‐Perylenemonoimide Host‐Guest ComplexesChemistrySelect, 2018, 3, 4699-4704.

248C)  W.-J. Wang, X. Wang, J. Cao, J. Liu, B. Qi, X. Zhou, S. Zhang, D. Gabel, W. M Nau, K. I. Assaf, H. Zhang. The Chaotropic Effect as an Orthogonal Assembly Motif for Multi-Responsive Dodecaborate-Cucurbituril Supramolecular NetworksCommun201854, 2098-2101. (Featured on the back cover page)

247C) K. I. Assaf, M. A. Alnajjar and W. M. Nau. Supramolecular Assemblies through Host–Guest Complexation between Cucurbiturils and an Amphiphilic Guest MoleculeChem. Commun. 201854, 1734-1737.





246A) A. I. Lazar, J. Rohacova, W. M. Nau, “Comparison of Complexation-Induced pKa Shifts in the Ground and Excited State of Dyes as Well as Different Macrocyclic Hosts and Their Manifestation in Host-Retarded Excited-Dye Deprotonation“, J. Phys. Chem. B,  2017, 121, 11390–11398.

245A)   K. I. Assaf, M. Florea, J. Antony, N. M. Henriksen, J. Yin, A. Hansen, Z.-w. Qu, R. Sure, D. Klapstein, M. K. Gilson, S. Grimme, W. M. Nau, “The HYDROPHOBE Challenge: A Joint Experimental and Computational Study on the Host-Guest Binding of Hydrocarbons to Cucurbiturils Allowing Explicit Evaluation of Guest Hydration Free Energy Contributions“, J. Phys. Chem. B,  2017, 121, 11144–11162.

244C) S. Peng, A. Barba-Bon, Y.-C. Pan, W. M. Nau, D.-S. Guo, A. Hennig, “Phosphorylation-Responsive Membrane Transport of Peptides”Angew. Chem. Int. Ed. 201756, 15742-15745; “Phosphorylierung reguliert den Membrantransport von Peptiden”Angew. Chem. 2017129, 15948-15951.

243C) A. Stahl, A. I. Lazar, V. N. Muchemu, W. M. Nau, M. S. Ullrich, A. Hennig, “A Fluorescent Supramolecular Chemosensor to Follow Steroid Depletion in Bacterial Cultures”Anal. Bioanal. Chem. 2017409, 6485-6494.

242A)  A. MukhopadhyayT. Hossen. GhoshA. KonerW. M. NauK. SahuJ. N. Moorthy, “Helicity-Dependent Regiodifferentiation in the Excited-State Quenching and Chiroptical Properties of Inward/Outward Helical Coumarins”.Chem. Eur.J. 20123, 14797-14805.

241C) G. H. Aryal, K. I. Assaf, L. Huang, W. M. Nau, K. W. Hunter, “Intracavity Folding of a Perylene Dye Affords a High-Affinity Complex with Cucurbit[8]uril“Chem. Commun.201753, 9242-9245.

240A)  A.-M. Resmerita, K. I. Assaf, A. I. Lazar, W. M. Nau, A. Farcas, “Polyrotaxanes Based on PEG-Amine with Cucurbit[7]uril, α-Cyclodextrin and its tris-O-methylated Derivative“, Eur. Polym. J.201793, 323-333.

239 A)  X. WangY. WangH. HeX. MaQ. ChenS. ZhangB. GeS. WangW. M. Nau F. Huang, “ Deep-Red Fluorescent Gold Nanoclusters for Nucleoi Staining: Real-Time Monitoring of the Nucleolar Dynamics in Reverse Transformation of Malignant Cells”. ACS Appl. Mat. Interf. 20179, 17799-17806.

238C) M. Nilam, A. Hennig, W. M. Nau, K. I. Assaf, “Gold Nanoparticle Aggregation Enables Colorimetric Sensing Assays for Enzymatic Decarboxylation”Anal. Methods 20179, 2784-2787.

237C)   S. M. Eiyrilmez, E. Bernhardt, J. Z. Dávalos, M. Lepšík, P. Hobza, K. I. Assaf, W. M. Nau, J. Holub, J. M. Oliva, J. Fanfrlíka, D. Hnyke, “Binary Twinned-icosahedral [B21H18]− Interacts with Cyclodextrins as a Precedent for its Complexation with other Organic Motifs“Phys. Chem. Chem. Phys., 201719, 11748-11752.

236C) K. I. Assaf, A. Hennig, S. Peng, D.-S. Guo, D. Gabel, W. M. Nau, “Hierarchical Host-Guest Assemblies Formed on Dodecaborate-Coated Gold Nanoparticles”Chem. Commun. 201753, 4616-4619.

235A) M. Nilam, P. Gribbon, J. Reinshagen, K. Cordts, E. Schwedhelm, W. M. Nau, A. Hennig, “A Label-Free Continuous Fluorescence-based Assay for Monitoring Ornithine Decarboxylase Activity with a Synthetic Putrescine Receptor”SLAS Discovery 201722, 906-914.





234A) A. I. Lazar, F. Biedermann, K. R. Mustafina, K. I. Assaf, A. Hennig, W. M. Nau, “Nanomolar Binding of Steroids to Cucurbit[n]urils: Selectivity and Applications”J. Am. Chem. Soc. 2016138, 13022-13029.

233A) A. Farcas, K. I. Assaf, A. Resmerita, S. Cantin, M. Balan, P. Aubert, W. M. Nau, “Cucurbit[7]uril-based fluorene polyrotaxanes”Eur. Polym. J. 201683, 256–264.

232A) K. I. Assaf, D. Gabel, W. Zimmermann, W. M. Nau, “High-Affinity Host-Guest Chemistry of Large-Ring Cyclodextrins” , Org. Biomol. Chem.2016, DOI: 10.1039/C6OB01161F .

231C) X. Wang, H. He, Y. Wang, J. Wang, X. Sun, H. Xu, W. M Nau, X. Zhang, F. Huang. “Active tumor-targeting luminescent gold clusters with efficient urinary excretion“, Chem. Commun. 201652, 9232-9235.

230C) A. F. Eftaiha, F. Alsoubani, K. I. Assaf, W. M. Nau, C. Troll, A. K. Qaroush, “Chitin-Acetate/DMSO as a Supramolecular Green CO2-Phile“, RSC Adv. 20166, 22090-22093.

229C) K. I. Assaf, O. Suckova, N. Al-Danaf, V. von Glasenapp, D. Gabel, W. M. Nau, “Dodecaborate-Functionalized Anchor Dyes for Cyclodextrin-Based Indicator Displacement Applications“, Org. Lett. 201618, 932-935.

228A) N. Al Danaf, R. Abi Melhem, K. I. Assaf, W. M. Nau, D. Patra, “Photophysical Properties of Neutral and Dissociated Forms of Rosmarinic Acid“, J. Lumin. 2016175, 50-56.

227A) D.-S. Guo, V. D. Uzunova, K. I. Assaf, A. I. Lazar, Y. Liu, W. M. Nau, “Inclusion of Neutral Guests by Water-Soluble Macrocyclic Hosts – A Comparative Thermodynamic Investigation with Cyclodextrins, Calixarenes, and Cucurbiturils”Supramol. Chem. 201628, 384-395.

226A) N. Saleh, M. B. Al-Handawi, M. S. Bufaroosha, K. I. Assaf, W. M. Nau, “Tuning Protonation States of Tripelennamine Antihistamines by Cucurbit[7]uril”J. Phys. Org. Chem. 201629, 101-106.






225A)    S. T. J. Ryan, R. M. Young, J. J. Henkelis, N. Hafezi, N. A. Vermeulen, A. Hennig, E. J. Dale, Y. Wu, M. D. Krzyaniak, A. Fox, W. M. Nau, M. R. Wasielewski, J. F. Stoddart, O. A Scherman, “Energy and Electron Transfer Dynamics within a Series of Perylene Diimide/Cyclophane Systems”J. Am. Chem. Soc. 2015137, 15299-15307.

224C)   K. I. Assaf, M. S. Ural, F. Pan, T. Georgiev, S. Simova, K. Rissanen, D. Gabel, W. M. Nau, “Water Structure Recovery in Chaotropic Anion Recognition: High-Affinity Binding of Dodecaborate Clusters to γ-Cyclodextrin”Angew. Chem. Int. Ed. 201554, 6852-6856. (Featured as back cover)

223C)  V. R. de la Rosa, W. M. Nau and R. Hoogenboom, “Thermoresponsive Interplay of Water Insoluble Poly(2-alkyl-2-oxazoline)s Composition and Supramolecular Host-huest Interactions” Int.J.Mol.Sci. 201516, 7428-7444.

222A)  V. R. de la Rosa, W. M. Nau and R. Hoogenboom, “Tuning Temperature Responsive Poly(2-alkyl-2-oxazoline)s by Supramolecular Host-Guest Interactions”Org. Biomol. Chem. 201513, 3048-3057.

221C)  F. Biedermann, D. Hathazi and W. M. Nau, “Associative Chemosensing by Fluorescent Macrocycle-Dye Complexes – A Versatile Enzyme Assay Platform Beyond Indicator Displacement”Chem. Commun. 201551, 4977-4980.

220A)  C. P. Carvalho, A. Norouzy, V. Ribeiro, W. M. Nau and U. Pischel, “Cucurbiturils as supramolecular inhibitors of DNA restriction by type II endonucleases”Org. Biomol. Chem. 201513, 2866-2869.

219A)  A. Farcas, A.-M. Resmerita, P.-H. Aubert, I. Ghosh, S. Cantin, W. M. Nau, “Synthesis, photophysical and morphological properties of azomethine persylilated α-cyclodextrin main-chain polyrotaxane”Macromol. Chem. Phys. 2015, doi: 10.1002/macp.201400543 .

218A)   A. Farcas, P.-H.  Aubert, J. Mohanty, A. I. Lazar, S. Cantin, W. M. Nau, “Molecular wire formation from poly[2,7-(9,9-dioctylfluorene)-alt-(5,5`-bithiophene/ cucurbit[7]uril)] polyrotaxane copolymer”Eur. Polym. J.201562, 124-129.

217A)   A. Norouzy, K. I. Assaf, S. Zhang, M. H. Jacob, W. M. Nau, “Coulomb Repulsion in Short Polypeptides”J. Phys. Chem2015119, 33-43.

216R)  K. I. Assaf and W. M. Nau, “Cucurbiturils: From Synthesis to High-Affinity Binding and Catalysis”Chem. Soc. Rev. 201544, 394-418. (Featured on front cover page)

215C)   A. Norouzy, Z. Azizi, W. M. Nau, “Indikatorverdrängungsassays in lebenden Zellen”Angew. Chem. 2015127, 804-808; “Indicator Displacement Assays inside Live Cells”Angew. Chem. Int. Ed201554, 792-795.

214A)   M. Sayed, F. Biedermann, V. D. Uzunova, K. I. Assaf, A. C. Bhasikuttan, H. Pal, W. M. Nau, J. Mohanty, “Triple Emission of p-Dimethylaminobenzonitrile – Cucurbit[8]uril Triggers the Elusive Excimer Emission”Chem. Eur. J. 201521, 691-696.





213R)   A. Norouzy, W. M. Nau, “Synthetic Macrocyclic Receptors as Tools in Drug Delivery and Drug Discovery”Drug Target Review 2014.

212A)   I. Ghosh, A. Mukhopadhyay, A. L. Koner, S. Samanta, W. M. Nau and J. N. Moorthy, “Excited-state properties of fluorenones: Influence of substituents, solvent and macrocyclic encapsulation” Phys. Chem. Chem. Phys. 201416, 16436-16445.

211A)   K. I. Assaf and W. M. Nau, “Cucurbiturils as fluorophilic receptors”, Supramol. Chem. 201426, 657-669.

210R)   F. Biedermann, W. M. Nau and H.-J. Schneider, “The Hydrophobic Effect Revisited-Studies with Supramolecular Complexes Imply High-Energy Water as a Noncovalent Driving Force”, Angew. Chem. Int. Ed. 2014, 53, 11158-11171.

209C)   J. Vázquez, P. Remón, R. N. Dsouza, A. I. Lazar, J. F. Arteaga, W. M. Nau and U. Pischel, “A Simple Assay for Quality Binders to Cucurbiturils”, Chem. Eur. J. 201420, 9897-9901.

208A)   S. T. J. Ryan, J. del Barrio, I. Ghosh, F. Biedermann, A. I. Lazar, Y. Lan, R. J. Coulston, W. M. Nau, and O. A. Scherman, “Efficient Host-Guest Energy Transfer in Polycationic Cyclophane-Perylene Diimide Complexes in Water”, J. Am. Chem. Soc. 2014136, 9053-9060.

207R)   G. Ghale, W. M. Nau, “Dynamically Analyte-Responsive Macrocyclic Host–Fluorophore Systems”Acc. Chem. Res201447, 2150-2159.

206C)   F. Biedermann, W. M. Nau, “Noncovalent Chirality Sensing Ensembles for Detection and Reaction Monitoring of Amino Acids, Peptides, Proteins, and Aromatic Drugs”Angew. Chem. Int. Ed. 201453, 11158-11171.

205R)   B. Mizaikoff, M. Lämmerhofer, J. Popp, S. He, W. M. Nau, K. Leopold, C. Kranz, J. W. Einax, “Trendbericht Analytische Chemie 2012/2013”, Nachr. Chem. 201462, 407-414.

204C)   G. Ghale, A. G. Lanctôt, H. T. Kreissl, M. H. Jacob, H. Weingart, M. Winterhalter, W. M. Nau, “Chemosensing Ensembles for Monitoring Biomembrane Transport in Real Time“Angew. Chem. Int. Ed. 201453, 2762-2765.





203A)   F. Biedermann, M. Vendruscolo, O. A. Scherman, A. De Simone, W. M. Nau, “Cucurbit[8]uril and Blue-box: High-energy Water Release Overwhelms Electrostatic Interactions”, J. Am. Chem. Soc. 2013135, 14879-14888.

202A)   V. Francisco, A. Piñeiro, W. M. Nau, L. García-Río, “The “true” affinities of inorganic metal cations to p-sulfonatocalix[4]arene: a thermodynamic study at neutral pH reveals a pitfall due to salt effects in microcalorimetry”, Chem. Eur. J. 201319, 17809-17820.

201A)   N. Abdali, E. Barth, A. Norouzy, R. Schulz, W. M. Nau, U. Kleinekathöfer, A. Tauch, R. Benz, “Corynebacterium jeikeium jk0268 constitutes for the 40 amino acid long PorACj, which forms a homooligomeric and anion-selective cell wall channel”, PLoS ONE 20138, e75651.

200A)   T.-C. Lee, E. Kalenius, A. I. Lazar, K. I. Assaf, N. Kuhnert, C. H. Grün, J. Jänis, O. A. Scherman and W. M. Nau, “Chemistry inside molecular containers in the gas phase”Nature Chem. 20135, 376-382.

199R)   N. Saleh, I. Ghosh, W. M. Nau, “Cucurbiturils in Drug Delivery and for Biomedical Applications in Supramolecular Systems in Biomedical Fields” H. J. Schneider, Ed., RSC Publishing, 2013, in press.

198A)   F. Biedermann, W. M. Nau, “Fässerweise Moleküle – Natürliche und synthetische Makrozyklen finden vielfältige Anwendungen in der Wirkstofforschung und Analytik”labor&more 2013, 30-35.

197A)   M. H. Jacob, R. N. Dsouza, I. Ghosh, A. Norouzy, T. Schwarzlose, W. M. Nau, “Diffusion-enhanced FRET and the Effects of External Quenchers and the Donor Quantum Yield”, J. Phys. Chem. B. 2013117, 185–198.





196A)   H. S. El-Sheshtawy, B. S. Bassil, K. I. Assaf, U. Kortz, W. M. Nau, “Halogen Bonding Inside a Molecular Container”, J. Am. Chem. Soc. 2012134, 19935-19941.

195A)   R. Sharma, M. Florea, W. N. Nau, K. Swaminathan, “Validation of Drug-Like Inhibitors against Mycrobacterium Tuberculosis L-aspatate α-decarboxylase Using Nuclear Magnatic Resonance (1H NMR)”, PLOS One 20127, e45947.

194A)   F. Biedermann, V. D. Uzunova, O. A. Scherman, W. M. Nau, A. De Simone, “Release of high-energy water as an essential driving force for the high-affinity binding of cucurbit[n]urils”J. Am. Chem. Soc. 2012134, 15318-15323.

193A)   S. Joshi, I. Ghosh, S. Pokhrel, L. Mädler, W. M. Nau, “Interactions of Amino Acids and Polypeptides with Metal Oxide Nanoparticles Probed by Fluorescent Indicator Adsorption and Displacement”, ACS Nano 20126, 5668-5679.

192C)   F. Biedermann, E. Elmalem, I. Ghosh, W. M. Nau, O. A. Scherman, “Strongly fluorescent, switchable perylene-bisdiimide (PDI) host-guest complexes with cucurbit[8]uril in water”Angew. Chem. Int. Ed. 201251, 7739-7743. (featured on cover page)

191C)   A. Farcas, I. Ghosh, W. M. Nau, “Effect of α-cyclodextrin on the optical and surface-morphological properties of pyrene-triazole azomethine oligomers”, Chem. Phys. Lett. 2012535, 120-125.

190R)   I. Ghosh, W. M. Nau, “The strategic use of supramolecular pKa shifts to enhance the bioavailability of drugs”Adv. Drug. Deliv. Rev. 201264, 764-783.

189R)   B. Mizaikoff, M. Lämmerhofer, J. A. C. Broekaert, J. Popp, B. Lendl, K. Leopold, F. W. Scheller, A. Yarman, S. Schumacher, N. Plumeré, A. Hennig, W. M. Nau, C. Kranz, J. W. Einax, “Trendbericht Analytische Chemie 2010/2011”, Nachr. Chem. 201260, 406-420.

188A)   G. Ghale, N. Kuhnert, W. M. Nau, “Monitoring Stepwise Proteolytic Degradation of Peptides by Supramolecular Domino Tandem Assays and Mass Spectrometry for Trypsin and Leucine Aminopeptidase”, Nat. Prod. Comm. 20127, 343-348.

187A)   M. Florea, S. Kudithipudi, A. Rei, M. José González-Álvarez, A. Jeltsch, W. M. Nau, “A Fluorescence-Based Supramolecular Tandem Assay for Monitoring Lysine Methyltransferase Activity in Homogeneous Solution”, Chem. Eur. J. 201218, 3521-3528.

186A)   R. N. Dsouza, A. Hennig, W. M. Nau, “Supramolecular Tandem Enzyme Assays”, Chem. Eur. J. 201218, 3444-3459.

185A)   S. Abraham, I. Ghosh, W. M. Nau, C. Chesta, S. J. Pas, A. J. Hill, R. G. Weiss, “In-cage and out-of-cage combinations of benzylic radical pairs in the glassy and melted states of poly(alkyl methacrylate)s”, Photochem. Photobiol. Sci. 201211, 914-924.

184R)   M. H. Jacob, W. M. Nau, “Short-distance FRET Applied to the Polypeptide Chain” in Folding, Misfolding and Nonfolding of Peptides and Small Proteins, R. Schweitzer-Stenner, Ed., John Wiley & Sons, Inc., Hoboken, New Jersey, U.S.A., 2012, 99-126.





183R)   R. N. Dsouza, U. Pischel, W. M. Nau, “Fluorescent Dyes and their Supramolecular Host-Guest Complexes with Macrocycles in Aqueous Solution”Chem. Rev. 2011111, 7941–7980.

182C)   M. Florea, W. M. Nau, “Strong Binding of Hydrocarbons to Cucurbituril Probed by Fluorescent Dye Displacement: A Supramolecular Gas-Sensing Ensemble”, Angew. Chem. 2011,123,9510-9514; Angew. Chem. Int. Ed. 201150, 9338-9342.

181C)   N. Saleh, Y. A. Al-Soud, L. Al-Kaabi, I. Ghosh, and W. M. Nau, “A Coumarin-based Fluorescent PET Sens or Utilizing Supramolecular pKa Shifts”, Tetrahedron Lett. 201152, 5249-5244.

180E)   W. Nau, A. I. Lazar, S. Joshi, “Book Review: Artificial Receptors for Chemical Sensors”, Angew. Chem. 2011123, 8622-8623, Angew. Chem. Int. Ed. 201150, 8472-8473.

179E)   W. Nau, “Book Review: Modern Molecular Photochemistry of Organic Molecules”, ChemPhysChem 201112, 2496-2497.

178A)   N. Saleh, M. A. Meetani, L. Al-Kaabi, I. Ghosh, W. M. Nau, “Effect of Cucurbit[n]urils on Tropicamide and Potential Application in Ocular Drug Delivery”, Supramol. Chem. 201123, 654-661.

177C)   C. Parente Carvalho, Vanya D. Uzunova, J. P. da Silva, W. M. Nau, U. Pischel, “A Photoinduced pH Jump Applied to Drug Release from Cucurbit[7]uril”, Chem. Commun. 201147, 8793-8795.

176R)   R. N. Dsouza, W. M. Nau, U. Pischel, “Complexation of Fluorescent Dyes by Macrocyclic Hosts” in Supramolecular Effects on Photochemical and Photophysical Processes, V. Ramamurthy, Y. Inoue, Eds., John Wiley & Sons, Inc., Hoboken, New Jersey, U.S.A. 2011, 87-114.

175A)   D.-S. Guo, V. D. Uzunova, X. Su, Y. Liu, W. M. Nau, “Operational calixarene-based fluorescent sensing systems for choline and acetylcholine and their application to enzymatic reactions”, Chem. Sci. 20112, 1722-1734.

174R)   W. M. Nau, M. Florea, K. I. Assaf, “Deep Inside Cucurbiturils: Physical Properties and Volumes of their Inner Cavity Determine the Hydrophobic Driving Force for Host–Guest Complexation”, Isr. J. Chem. 201151, 559-577.

173A)   W. M. Nau, O. A. Scherman, “The World of Cucurbiturils – From Peculiarity to Commodity (Guest Editorial)”, Isr. J. Chem. 201151, 492-494; featured on cover page.

172A)   G. Ghale, V. Ramalingam, A. R. Urbach, W. M. Nau, “Determining Protease Substrate Selectivity and Inhibition by Label-Free Supramolecular Tandem Enzyme Assays”, J. Am. Chem. Soc. 2011133, 7528-7535.

171C)   H. S. El-Sheshtawy, U. Pischel, W. M. Nau, “Solvent Polarity Affects H Atom Abstractions from C–H Donors”, Org. Lett. 201113, 2694-2697.

170A)   J. N. Moorthy, S. Samanta, A. L. Koner, W. M. Nau, “Steady-state photochemistry (Pschorr cyclization) and Nanosecond Transient Absorption Spectroscopy of Twisted 2-Bromoaryl Ketones”, Pure Appl. Chem. 201183, 841-860.

169A)   A. Farcas, I. Ghosh, V. C. Grigoras, I. Stoica, C. Peptu, W. M. Nau, “Effect of Rotaxane Formation on the Photophysical, Morphological, and Adhesion Properties of Poly[2,7-(9,9-Dioctylfluorene)-alt-(5,5′-Bithiophene)] Main Chain Polyrotaxanes”, Macromol. Chem. Phys. 2011212, 1022-1031.

168A)   A. L. Koner, I. Ghosh, N. Saleh, W. M. Nau, “Supramolecular Encapsulation of Benzimidazole-Derived Drugs by Cucurbit[7]uril”, Can. J. Chem. 201189, 139-147.

167C)   A. L. Koner, C. Márquez, M. H. Dickman, W. M. Nau, “Chemoselektive Photoreaktionen mithilfe von Übergangsmetallen in Cucurbiturilen”, Angew. Chem. 2011123, 567-571; “Transition Metal-Promoted Chemoselective Photoreactions at the Cucurbituril Rim”, Angew. Chem. Int. Ed. 201150, 545-548; featured on cover page.





166A)   D. Verbaro, I. Ghosh, W. M. Nau, R. Schweitzer-Stenner, “Discrepancies between Conformational Distributions of a Polyalanine Peptide in Solution Obtained from Molecular Dynamics Force Fields and Amide I′ Band Profiles”, J. Phys. Chem. B2010, 114, 17201-17208.

165A)   J. Mohanty, K. Jagtap, A. K. Ray, W. M. Nau, H. Pal, “Molecular Encapsulation of Fluorescent Dyes Affords Efficient Narrow-band Dye Laser Operation in Water”, ChemPhysChem 201011, 3333-3338.

164A)   R. Meyer, A. F.-P. Sonnen and W. M. Nau, “Phase-Dependent Lateral Diffusion of α-Tocopherol in DPPC Liposomes Monitored by Fluorescence Quenching”, Langmuir 201026, 14723-14729.

163R)   W. M. Nau, “Supramolecular Capsules: Under Control”, Nature Chemistry 20102, 248-250.

162A)   I. Ghosh, N. Saleh and W. M. Nau, “Selective time-resolved binding of copper (II) by pyropheophorbide-a methyl ester”, Photochem. Photobiol. Sci. 20109, 649-654.

161C)   U. Pischel, V. D. Uzunova, P. Remón, W. M. Nau, “Supramolecular Logic with Macrocyclic Input and Competitive Reset”, Chem. Commun. 2010, 46, 2635-2637.

160A)   V. D. Uzunova, C. Cullinane, K. Brix, W. M. Nau, and A. I. Day, “Toxicity of Cucurbit[7]uril and Cucurbit[8]uril: An Exploratory in vitro and in vivo Study”, Org. Biomol. Chem20108, 2037-2042.

159A)   J. Cui, V. D. Uzunova, D.-S. Guo, K. Wang, W. M. Nau, Y. Liu, “Effect of Lower-Rim Alkylation of p-Sulfonatocalix[4]arene on the Thermodynamics of Host–Guest Complexation”, Eur. J. Org. Chem. 2010, 1704-1710.

158A)   M. Florea and W. M. Nau, “Implementation of Anion-Receptor Macrocycles in Supramolecular Tandem Assays for Enzymes Involving Nucleotides as Substrates, Products, and Cofactors”, Org. Biomol. Chem. 20108, 1033-1039.